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After struggling with depression in a mental hospital, Hunter "Patch" Adams (Robin Williams) decides he wants to become a doctor. He enrolls at Virginia Medical University but is disillusioned by the school's clinical perspective on patient care. With the aid of a wealthy friend, Adams opens his own medical clinic for those without insurance. He forms a deep bond with fellow medical student Carin Fisher (Monica Potter) before a tragedy causes Adams to re-evaluate his approach.